Standard Growth Curve of Japanese using Non-Linear Growth Model

Norio Shinozuka, Takashi Nakamura, Munehiro Hirayama
Tokyo Metropolitan Government Maternal and Child Health Service Center
Tokyo Research Network of Perinatal Medicine
Acta Neanatoligica Japonica 30(3)433-441,1994



abstract
The standard fetal weight growth curve was established using huge data accumulated in the n~atal detabase at Tokyo Metropolitan Government Maternal and Child Health Service Center since . Out of 69666 cases, 12093 cases were excluded due to maternal or fetal complication, 269 cases were uded as outlying data by statistical analysis and 57304 cases were used for making standard growth curve. The statistical analysis of ANOVA procedure showed that the factors of parity and sex were related to fetal weight significantly after 32 weeks of gestation. This result suggested that 32 weeks of ation was a turning point of fetal weight growth. Therefore, the growth curve was divided into female male curve with adding primipara and multipara curves after 32 weeks of gestation. Considering for [ weight estimation by ultrasound during pregnancy, we made a standard curve without dividing e related to parity and sex. Non-linear regression using logistic model divided at 32 weeks showed fit to the original data. Comparison between our new curve and Nishida's growth curve indicated latter curve had a wide range of l.5 SD, especially-I .5 SD range was wide at 33 to 37 weeks of ation. This result should be caused by the fact that the latter curve was made without excluding ;rnal complication such as gestosis. It suggested that our new curve, that was established by using statistics and non-linear model, indicated an ideal fetal growth in utero.
Keywords Fetal growth, Standard curve, non-lenear regression, Logistic model, Growth model

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